2021年9月15日 星期三

Can Herd Immunity End the COVID-19 Pandemic?

 The COVID-19 pandemic has created an unprecedented situation worldwide, causing millions of deaths and significant damage to the world economy. For more than a year, people have heard and hoped for herd immunity that may be achievable in the long-term with near-universal vaccination. Do the low infection rates around the world suggest that COVID-19 herd immunity is just around the corner?

It's been more than a year since the world first encountered the highly contagious SARS-CoV-2 virus. The resilient coronavirus has managed to proliferate and spread across communities despite social distancing measures and other precautions to stop transmission. Now that multiple COVID-19 vaccines have been authorized and rolled out for use, people are positive about developing "herd immunity". According to the United States Centers for Disease Control and Prevention, herd immunity refers to the sufficient proportion of the population that become immune to a particular disease due to the development of antibodies either from vaccination, or previously contracting the disease.

If majority of the population becomes immune after vaccination, they would not be able to spread the infection further to vulnerable population. Thus, herd immunity ensures the protection of the remaining population and reduces the risks of transmission. Developing herd immunity seems like a practical solution for a fight against COVID-19 infection and therefore vaccine inoculation drives are at full swing. There isn't any "magic threshold" but, usually 50-90% population needs immunity before the infection rates start to decline, however the number can vary depending on how contagious the virus is. For COVID-19, the herd immunity is estimated to be between 70-90%, given that the immunity lasts longer.

How Can We Achieve Herd Immunity with SARS-CoV-2?
While wearing masks in public, social distancing, and reducing the level of interaction can help to slow down the infection rates, the virus might mutate as communities open up broadly and become even more contagious. However, there are two ways to achieve herd immunity, either the large proportion of the population gets vaccinated or infected with the virus. Achieving herd immunity in the United States would require more than 230 million Americans to get infected. However, this could lead to more hospitalization, ICU admissions, and cost millions of lives. The patients who suffer from mild infection might also have severe illness for weeks or other long-term side-effects. Therefore, achieving herd immunity through infection becomes painfully ill-conceived thought.

Another way to achieve a herd-immunity threshold is through high vaccination rates, immunizing mass population so that the society could return to normalcy. Vaccine inoculation to 70-80% of the population for COVID-19 virus will not only protect the vulnerable populations at high risks but also extend the immunization benefits beyond the directly targeted population. Some of the vulnerable groups that depend on herd immunity for achieving protection against the diseases include:
• People with compromised immune functioning
• People on chemotherapy treatments
• People suffering from HIV
• New-borns and infants
• Elderly people

Why is Vaccine Equity Essential to Develop Herd Immunity?
While more than 1.65 billion doses of vaccines have been administered in rich nations, only 0.8% of all vaccines have been allocated to poor countries. Wealthy nations have focused more on securing vaccines for their populations while ignoring to make investments in cooperative initiatives for fair distribution of vaccines across the globe. However, the global coverage of vaccines is imperative to manage the transmission of COVID-19. The imbalance is creating a need to move past beyond outdated charitable models and instead focus on amplifying the manufacturing and distribution capacity throughout the world in order to increase immunization. The international community need to empower nations by technology transfer or passing intellectual property waivers in the World Trade Organization for vaccines so that poor countries can produce their own vaccines.

Vaccine nationalism may not be the best solution to defeat the spread of virus. As wealthy countries are rolling out domestic vaccination plan, the new and emerging variants are reducing the effectiveness of vaccines against the virus. Even with vaccination shields, the rich countries are vulnerable, and their economies are also at risk. The International Chamber of Commerce predicts that if poor countries are not immunized, the global economy may lose across USD9.2 trillion whereas funding for the Access to COVID-19 Tools (ACT) would require only USD22.9 billion. Besides, global allocation might postpone the domestic vaccine roll-out but doing so will contribute to global herd immunity.

Obstacles for Achieving Herd Immunity
• Vaccine Hesitancy
Some people are reluctant to get vaccinated due to lack of information about the safety of vaccines, or widespread misinformation about them. Besides, religion, political party affiliation, or ethical obligations are adding to vaccine hesitancy. According to a study, one in four young adults do not want to get vaccinated, jeopardizing the health of older unvaccinated adults and facilitating the rise of vaccine variants. However, education and public health messaging can encourage youth and young adults to reduce vaccine hesitancy.

• Emergence of New Variants
As long as there are unvaccinated populations across the world, the COVID-19 virus will continue to mutate and become more dangerous. Even if the wealthy nations successfully achieve herd immunity, the risk of transmission would not reduce, and the booster shots might be required to ensure protection against the variants that could evade the immune response provoked by current vaccines. Besides, the emergence of new strains across the world due to mutation in the spike protein of the coronavirus may not induce antibody response in the infected person.

• Delayed Arrival of Vaccinations for Children
Children have been less susceptible to the coronavirus but not all have escaped unscathed. Besides, infected youngsters have unintentionally passed the illness to others, and thereby increasing the overall infection rates. Although many vaccines are under trial to determine their efficacy against the coronavirus for children, it is only a matter of time when the virus mutates and start attacking the young population. Brazil's devastating wave of coronavirus is targeting younger age groups and pregnant women. Despite the growing paranoia, many young mothers are not willing to seek vaccination for their children due to misinformation about vaccines and their potential side effects.

• Limited Evidence on Immunity Post-COVID Infection
Some studies suggest that infection with SARS-CoV-2 offers protection against the virus for at least a year. As the antibodies enhance immune response and confer strong resistance against variants of coronavirus, getting infected guarantees some level of protection. The level of immunity that vaccines offer varies depending upon how one's body responds to it. A single dosage provides some level of protection, but second dosage is essential to achieve full immunity. While scientists have evaluated the efficacy of vaccines for most people in the first few months, they do not have data on the long-term immunity since many vaccines haven't even completed a year of follow-up.

Conclusion
Vaccinating as many people as possible can be significant in slowing down the spread of the COVID-19. However, achieving herd immunity would not guarantee complete eradication of the coronavirus as it is highly infectious and continues to evolve. Herd immunities vary at global, national, and community level, and change over time, therefore even when the threshold is attained, there would be small outbreaks due to uneven vaccine coverage.

According to TechSci research report on "Global Coronavirus Vaccine Market By Infection Type (SARS-CoV-2, SARS-CoV, MERS-CoV), By Vaccine Type (Virus Vaccine, Viral Vector Vaccine, Nucleic Acid Vaccine, Protein Based Vaccine and Others), By Product Type (Monovalent Vaccine v/s Multivariant Vaccine), By Route of Administration (Intramuscular, Oral, Intranasal), By Patient Type (Adults v/s Pediatric), By End User (Hospitals, Clinics, Research Institutes, Others), By Region, Competition Forecast & Opportunities, 2026", the global coronavirus vaccine market is anticipated to grow at a formidable CAGR during the forecast period owing to factors such as the rising incidences of coronavirus infection as well as introduction of new vaccines in the market.

According to another TechSci research report on "Global Coronavirus Diagnostics Market By Type of Test (Molecular v/s Serology), By User (Multiple v/s Single), By Full Test Time (1 Hour - 12 Hours, Less Than 60 Minutes, 13 Hours - 24 Hours, More Than 1 Day), By End User (Hospitals, Public Health Labs, Private or Commercial Labs, Physician Labs, Others), By Region, Competition Forecast & Opportunities, 2026", the global coronavirus diagnostics market is projected to reach a market value of USD15.57 billion by 2026. The growth can be attributed to the increasing incidences of coronavirus cases and rising use of diagnostic testing kits for the same.


Negatives Health Effects of Alcohol

 Alcohol is a liquid compound, resulting from sugar fermentation of different foods such as malted barley, potatoes, cinder or grapes. At lower doses, the beverage acts as stimulant while in high doses, it works as a depressant to the central nervous system. Any adult of 21 years and above can legally obtain alcohol in the United States. Negatives effect of alcohol on the human body are numerous and the results commence immediately after consumption. Even though small quantities of alcohol can get out of the body through breathing and urine, most of the product gets absorbed into the bloodstream

The more alcohol one takes, the more the effects it has on the body systems. Many people are not conversant with what constitutes a standard drink and the measurement of alcohol intake, which is one 12- ounce bear with 5% alcoholic content. Below are some of the negative effects on body systems

Effect on the central nervous system

Alcohol interferes with the brain communication causing altered behavior and mood as well as inhibit the capacity to think clearly. Also, high alcohol intake can significantly affect motor functioning through its effects on the brain. Poor coordination, Slurred speech as well poor memory are other negatives of alcohol on the rest of the central nervous system. More drastic and harmful effect on the central nervous system results from prolonged and excessive alcohol consumption. These effects include odd sensation, numbness on feet and hands as well as pain resulting from the damage on the central nervous system

Circulatory system

Alcohol affects Heart which is one of a vital organ of the circulatory system. Heart complication is very common on individuals with excessive and prolong drinking habits as well as those who drink too much alcohol in a single sitting. The adverse effects of alcohol on the heart include high Blood pressure, heartbeat irregularity, abnormal heart muscle stretching and stroke. Research has who moderate alcohol drinking is good for heart health. However, excessive alcohol drinking increases the risks of complication such as heart failure and heart attack

Liver

Liver damage or cirrhosis is the common condition associated with the extreme and prolonged use of alcohol. The state involves scarring of the liver tissues by alcohol affecting its functions such as ensuring robust immune system and cleaning the blood. Excessive alcohol also cause fibrosis, alcoholic hepatitis as well as fatty liver

Digestive system

Alcohol consumption is known to have a significant effect on the human digestive system. The beverage can damage gum, tongue as well as salivary glands significantly. Also, alcohol causes tooth decay among heavy drinkers and alcoholics as well as accelerates esophageal problems and stomach ulcers. Excessive alcohol drinking causes the inflammation of the pancreas or pancreatitis, which can result in permanent damage to the organ

Reproduction

Alcohol abuse among woman can cause irregular and disrupted menstrual cycle, and in extreme cases case can led to infertility. Pregnant woman should avoid alcohol as much as possible due to birth and pregnancy complication as well as to protect the unborn child from the fetal alcohol system disorder or fetal alcohol syndrome. The condition affects the child mentally and physically

Other adverse effects on human health include erection dysfunction on men, weak immune system, and low production of testosterone in men which diminish the development of male physical characteristics as well as obesity and high risk of prostate problems. It's advisable to lower alcohol intake or abstain from drinking to improve and reverse these adverse effects on the body



The Many Health And Fitness Benefits Of Sports

 If you are on this page, chances are that you are interested in finding out the health and fitness benefits of taking part in sports. If you want to take up a sport, you are reading the right article. As a matter of fact, if you take part in your favorite sport, you can enjoy a number of health and fitness benefits. In this article, we are going to talk about some of these benefits. Read on to find out more.

Generally, taking part in physical activities can help you improve your health and fitness. Most people don't feel like going to the gym or using a treadmill, but many of them will happily take part in physical sports such as football. The thing is that it is the element of fun that makes it possible for people to get out and take part in a sport.

According to most people, engaging in physical activity helps improve their mental health and overall well-being. As a matter of fact, there are many reasons why you may want to engage in sport. For example, physical activities can help you reduce your body fat, improve your stamina, and increase your bone strength. These are some solid reasons why you should be physically active.

Given below is the description of some of the common health and fitness benefits of taking part in a sport.

  • If you remain active, you can reduce your body fat and monitor your body weight.
  • Physical activities allow you to get the satisfaction of remaining fit.
  • If you want to fight anxiety and depression, nothing can work better than engaging in your desired support on a regular basis.
  • If you play sports, you can set goals and challenge yourself on a regular basis.
  • If you engage in physical activities, you can improve your flexibility, balance, and coordination.
  • Taking part in sports may help you to give a boost to your concentration and stamina.
  • It can also help you to become more active in real life.
  • Taking part in physical activities on the field can help you make new friends who will share the same interests as you.
  • Taking part in sports can help families get together and reap all the benefits of physical activities.
  • If you want to adopt a healthy lifestyle, make sure you take part in your decide sport.
Long story short, this was a description of some common benefits of taking part in sports. If you have never taken part in this type of physical activity in your life, now is the right time to get started. After all, nothing is more important to you than your own health and overall well-being. Hopefully, these benefits will inspire you to get out of your comfort zone and do something physical.

Getting latest sports news is as easy as checking out Fun88 Sports. This website gives you latest news about your favorite sports.




Here Is What You Should Know About Beta-Glucans?

 Beta-glucans refer to a type of polysaccharides, which are found in the cell walls of mushrooms like Maitake and Reishi. Apart from this, they occur naturally in algae, yeast, bacteria, and barley, to name a few. This type of fiber is soluble and offers a lot of health benefits. For example, they are good for the bacteria in your digestive tract as these bacteria help your immune system functionality, blood sugar management, and cholesterol levels. Let's find out more about it.

How Does it Work?

Since beta-glucans is a type of soluble fiber, it dissolves in water partially and reduces the movement of food in your guards. Therefore, your body takes more time to absorb carbohydrates and makes you feel full for longer. of time.

Since food is digested slowly in your body, this process can help you to maintain your blood sugar levels. Since soluble fiber is indigestible, it passes through your digestive tract.

Apart from this, these glucans come with high antioxidant properties. Therefore, it can generate short-chain fatty that has a positive impact on your metabolism.

Beta-Glucan Prominent Benefits

According to experts, These offer a number of health benefits. Some of these benefits are listed below:

Reduces triglycerides and cholesterol in your body for your heart health

Helps you maintain your body weight by supporting blood sugar levels and increasing satiation

Develop the growth of gut bacteria and give a boost to short-chain fatty acids

Empower your immune system and prevent fatigue infection and stress

Moisturizers your skin and make it former

Here is How you can add Beta-glucans to Your Diet

As far as the availability of glitter glue is concerned, you can find them in the following types of foods. You can have these foods if you want to consume beta-glucans to reap all of the benefits listed above.

  • Seaweed
  • Barley fiber
  • Cereals
  • Whole grains and oats
  • Functional mushrooms like Shiitake, Turkey Tail, Maitake, and Reishi
Since you cannot produce beta-glucans in your body, you can purchase or get functional mushrooms to enjoy health and wellness benefits. Since reishi mushrooms can activate your immune system, this can help you empower your weak immunity and regulate an overactive immune system.

If you want to make these as part of your diet, we suggest that you eat functional mushrooms on a regular basis. Alternatively, you can purchase mushroom powders. They are also available in liquid forms, such as oil.

Although research studies are still going on to find out more about the health benefits of Beta-glucans, we still have enough evidence to support the idea. Therefore, if you want to enjoy a functional immune system and great gut health, we suggest that you give a go to beta-glucans in your desired form.

In short, this was a brief introduction to beta-glucans reishi mushrooms and several benefits that they offer. Therefore, it makes sense to eat reishi mushrooms on a regular basis.

Reishi Beta Glucan offers a lot of health benefits. For ease of use, you can go for Ganoderma lucidum spore oil to cover your needs.



Our First Line of Health Defense Is Our Immunity

Our immune system is our body's first line of defense against foreign invaders. It is our body's natural defense and, without it, we wouldn't stand a chance against microorganisms such as fungus, viruses, parasites and bacteria.

These pesky, health destroying intruders hide out everywhere and it is our immune system working around the clock that sets up protective barriers preventing them from entering our body.

Should one sneak by, our immune system has a back-up plan that kicks in and sends out an array of chemicals and proteins along with a host of white blood cells, all seeking to find and attack the foreign antigen before it has time to reproduce.

A strong immune system helps keep all health problems at bay from dangerous diseases to common colds. When working at peak performance, it recognizes and responds to millions of antigens producing what's needed to eradicate them.

Dr. Bruce Polsky MD, St. Luke's Roosevelt Hospital in N.Y. states, "we are endowed with a great immune system designed to evolutionarily keep us healthy."

However, when we continually engage in unhealthy habits/lifestyles we weaken our immune system. These dangerous actions open the door to foreign invaders and the end result is, we get sick.

Simple healthy tactics such as washing our hands often and avoiding close contact with those affected with illness are obvious solutions we can employ that help keep us from getting sick.

Taking a pro-active stance to boost our immune system is the other.

Here's a few tips that help keep the immune system humming in tip-top shape:

Nutrient dense diet -

Vegetables, fruits and other plants contain natural substances known as phytochemicals (natural compounds found in plants) that give them their color and flavor. These phytochemicals act as powerful antioxidants neutralizing free radicals before they can create damage. They also serve as soldiers, supporting the immune system and the death of damaged cells, protecting the body from damage and creating new healthy cells.

All illnesses, diseases and infections are harder to ward off if the body is lacking nutrients/malnourished. It's best to choose and enjoy foods from all food groups including some protein with every meal and snack.

Proper Exercise -

The immune system is very responsive to exercise. After diet, it is one of the pillars that contribute to overall great health and strong immunity. It activates the sympathetic nervous system and increases heart rate, blood pressure and breathing, making us feel better and more energetic.

It kicks our circulation in, reduces anxiety and stress, slows the aging process, helping us to live longer and better.

Recent studies performed at the University of California-San Diego; School of Medicine revealed that 20 minutes of exercise provides our body with anti-inflammatory effects that, in turn, boost immunity.

Reduce and avoid stress -

Our state of mind does affect our health. Long-term, chronic stress increases the chance of illness because it depresses the immune system. This type of emotional and mental wear and tear ravages our immunity and our health.

Deep breathing, meditation and exercise all help to reduce the effects of chronic stress.

Adopt a Healthy Attitude -

Although we cannot control all events in our lives, we can control our feeling/attitude/response towards them. A positive, good attitude (seeing the glass half-full rather than half-empty), expressing gratitude every day in all situations works to strengthen our immune system and increases all chances for a positive outcome.

Laughter heals -

Laughter is powerful, more than we realize. It boosts our immunity because it is empowered to decrease our stress hormones, increase infection fighting antibodies and trigger the release of "happy" endorphins.

As a health bonus, it also works our abs, lowers our blood pressure, improves cardiac health and boosts our T-cells. It truly is "the best medicine."

According to Dr. Lee Berk, PH, Pro Loma Linda School of Medicine, "The best clinicians understand that there is an intrinsic physiological intervention brought about by positive emotions such as mirthful laughter, optimism and hope." Laugh often, it's free for everyone.

Quality Sleep -

Sleep is a major component towards being healthy. It's the downtime the body uses to rebuild and restore. Lack of it results in a weak immune system for a variety of reasons. One major issue is that less cytokines are produced. Cytokines are proteins released during sleep that target infection and inflammation creating an immune response.

Ongoing studies prove that those suffering from chronic sleep loss are more likely to get sick after exposure to viruses.

If your sleep cycle is interrupted and your schedule allows, try making up the loss with a nap. Two naps daily, one in the morning and one in the afternoon (no longer than 30 minutes duration) decreases stress and offsets any negative effects created by sleep deprivation on the immune system.

Step into the Sun -

The sun/natural sunlight is the body's major provider of Vitamin D. Vitamin D helps the body produce antibodies which in turn, boost the healthy functioning of our immune system.

For example, one major reason for respiratory issues is low levels of vitamin D. A simple fresh air walk in the sunlight of approximately 20-30 minutes helps ensure enough Vitamin D is produced by the body.

Fresh air and sunshine help heal us.

A strong immune system doesn't make us invincible but throws the odds in our favor. Therefore, our first line of defense against life's many health challenges is a healthy lifestyle.

Our immune system gets a true boost when we adopt an "attitude of gratitude," don our fitness gear, enjoy and share many good belly laughs and focus on healthy foods!

It's a true warrior when it comes to decreasing our chances of falling ill and provides the extra strength needed to fight any invader that finds its way through. It's a good thing.

Carolyn Hansen -Your Go To Health & Fitness Specialist

"I help clients take charge of their health before circumstance removes the option. If your quest for a life of true physical and mental well-being is a journey I'll put you in the driver's seat."

For tools and resources to achieve this visit: Carolyn Hansen Fitness




Essence of Wellness

 In the article why fitness is the essence of overall wellness, author Aravind Shiyaraman begins by talking about what real fitness. He states that achieving fitness is actually not that difficult. And you can't judge the fitness of a person by looking at someone. Someone who looks fit on the outside may actually be very unfit on the inside. There is more that goes into it. For example the health of your heart. This component is probably one of the most important aspects of overall wellness. This is because your heart is connected to so many things in your body. With a healthy heart you increase your lung capacity, have stronger bones, have stronger muscles, and other things like weight loss. So when you have a healthy heart, you are then on the road to a healthy body.

Aravind goes on to talk about the obsession with fitness now a days. He states that definition of fitness is actually the ability to carry out daily chores. This means without getting easily tired. While this use to not be an issue back in the days, recently it's become very common to get fatigued from daily chores. That is why fitness has become so popular. Lack of physical activity and lifestyle diseases have contributed to the increased talk about fitness. More and more people need to find ways to switch up their lives in order to better their health.

So why is fitness so important? Because of sedentary lifestyle so common today, it has increased diseases. Although many people know that it is important to stay active, many people are unable to because of their busy lifestyles. With work and raising a family, fitness has been put on the back burner. But it is crucial with everyone get up and get moving. Heart disease is the leading cause of death. Things like stroke and diabetes all are connected to lack of exercise. In order to prevent these diseases get moving and try to stay as active as possible!

There are than physical benefits of staying fit. Although keeping healthy weight and preventing diseases is important, fitness also provides psychological benefits as well. The hormone endorphins are actually released when you exercise. This is the feel good hormones. Because these are released when you exercise, you mood will elevate. By increasing endorphins it can actually help fight depression, anxiety, and lack of self esteem!